常江
常江，男，中国科学院上海硅酸盐研究所研究员，博士生导师。
人物简介
男，博士、研究员，博士生导师，美国生物材料协会、国际组织工程学会、新西兰显微镜学会、澳大利亚/新西兰基质生物学学会、中国生物材料学会会员。
1982年毕业于陕西科技大学化工一系。
1985年赴德国留学，1991年在德国达姆施达特工业大学获博士学位，从1991年4月至1993年6月在德国卢卑克医科大学做博士后研究，从事活性人造皮肤作为皮肤创伤修复模型的研究。
1993年7月至1997年6月在新西兰奥克兰大学任研究员，从事软骨细胞与生物材料相互作用机理方面的研究。1996年获新西兰职业华人杰出成就奖。
1997年至1999年在美国纽约大学受聘为研究助理教授。主要研究课题包括以胶原蛋白材料为载体进行软骨细胞移植修复软骨损伤、生物陶瓷活性骨损伤修复材料的研究。
1999年至2000年在美国强生损伤修复技术中心任研究员，从事生物材料和骨科组织工程学方面的研究开发工作。
2000年12月获中国科学院“引进国外杰出人才”（百人计划）基金，应聘回国，到中国科学院上海硅酸盐研究所从事科研工作。
主要研究领域介绍
（1）可降解生物活性骨修复材料的研究
（2）作为药物载体的生物材料以及药物控制释放的研究
（3）纳米生物材料制备技术研究
专著
1. Chengtie 吴语 Jiang Chang. Yin Xiao. “Advanced bioactive inorganic materials for bone regeneration and drug delivery" Publisher. CRC Press and Taylor \u0026 Francis. January
2. Kaili Lin, Jiang Chang. Chapter 6: Preparation and mechanism of novel bioceramics with controllable morphology and crystal growth,in “Advanced Bioactive Inorganic Materials for Bone Regeneration and Drug Delivery”, CRC press, March
3. Jiang Chang, Wenguo Cui, Yue Zhou, Lei Chen, Fabrication of Fibrous Scaffolds for Tissue Engineering by Electrospinning Techniques, Chapter 15 in The Handbook of Intelligent Scaffold for Regenerative Medicine, Ed. Gilson Khang, Publishers: pan Stanford Publishing
4. Wenguo Cui, Jiang Chang, Paul Dalton, Electrospun Fibers For Drug Delivery, in Comprehensive Biomaterials, Ed. Paul Ducheyne, Kevin E. Healy, Dietmar E. Hutmacher, David E. Grainger and C. James Kirkpatrick, Publisher: Elsevier Science
5. Jiang Chang, Yanling Zhou, Yue Zhou, Surface modification of bioactive glasses, in Bioactive Glasses, Ed. Heimo Ylänen, Publishers: Woodhead Publishing ltd
6. Chengtie Wu, Jiang Chang, Hala Zreiqat. “Engineered Ca-Si based ceramics for skeletal tissue reconstruction”. In Book: "Biomaterials for Bone Regenerative Medicine" by editors: N.Sooraj Hussain and J. D. Santos. Publishers: Trans Tech Publishers (Ttp), Switzerland
7. Jiang Chang, Daming Zhang, Lingzhi Ye. “Biodegradable bioceramics/polymer composites for tissue regeneration” in 《surface 设计 and Modification of Biomaterials for Clinical Application-Geometry of Material Surfaces, Cell Affinity and Immobilization of CAMs and Tropic Factors》 , Editor: Junzo Tanaka，Publisher: Research Signpost,
8. Jiang Chang, Lei Chen. “Silicate-based bioactive materials for bone regeneration” in Biomaterials in Asia. Ed. Tetsuya Tateishi, World Scientific Publishing Co Pte ltd
9. Ying-Jie Zhu, Jiang Chang. “Microwave-assisted Synthesis and Processing of Biomaterials” in NanoScience in Biomedicine. Ed. Donglu Shi, Publisher: Springer
期刊论文
1. Xiaoguo Liu, Kaili Lin, Chengtie Wu, Yueyue Wang, Zhaoyong Zou, Jiang Chang*. Multilevel hierarchically ordered artificial biomineral. SMALL
2. Haiyan Li, Ke Xue, Ni Kong, Kai Liu*, Jiang Chang*. Silicate bioceramics enhanced vascularization and osteogenesis through stimulating interactions between endothelia cells and bone marrow strOMAL cells. Biomaterials
3. Chengtie Wu, Pingping Han, Xiaoguo Liu, Mengchi Xu, Tian Tian, Jiang Chang*, Yin Xiao*. Mussel-inspired β-tricalcium 磷酸盐 bioceramics with Ca-P/polydopamine hybrid nanolayer: preparation, formation mechanism and improved cellular bioactivity. Acta Biomaterialia
4. Mengchi Xu, Dong Zhai, Jiang Chang*, Chengtie Wu*. In vitro assessment of 3D-Plotted nagelschmidtite bioceramic scaffolds with varied macropore morphology. Acta Biomaterialia
5. Chengtie Wu, Yinghong Zhou, Mengchi Xu, Pingping Han, Lei Chen, Jiang Chang*, Yin Xiao*. 铜containing mesoporous bioactive glass scaffolds with multifunctional properties of angiogenesis capacity, osteostimulation and antibacterial activity. Biomaterials
6. Chengtie Wu*, Wei Fan, Jiang Chang*. Functional mesoporous bioactive glass nanospheres: synthesis, apatite mineralization, controllable delivery of doxorubicin and inhibitory effect on bone cancer cells. Journal of Materials 化学
7. Chengtie Wu, Pingping Han, Mengchi Xu, Xufang Zhang, Yinghong Zhou, Guangda Xue, Jiang Chang*, Yin Xiao*. Nagelschmidtite bioceramics with osteostimulation property: material chemistry activating osteogenic genes and WNT signalling pathway of human bone marrow stromal cells. Journal of Materials 化学 B
8. Chengtie Wu*, Minghui Zhang, Dong Zhai, Jianding Yu, Yan Liu, Huiying Zhu, Jiang Chang*. Containerless processing for preparation of akermanite bioceramic spheres with homogenous structure, tailored bioactivity and degradation. Journal of Materials 化学 B
9. Chen Wang, Kaili Lin, Jiang Chang*, Jiao Sun*. Osteogenesis and angiogenesis induced by porous b-CaSiO3/PDLGA compositescaffold via activation of AMPK/ERK1/2 and pi3k/Akt pathways. Biomaterials
10. Haiyan Li, Jiang Chang*. Stimulation of proangiogenesis by 钙 silicate bioactive ceramic. Acta Biomaterilia.
11. He Xu, Haiyan Li*, Jiang Chang*. Controlled drug release from polymer matrix by patterned electrospun nanofibers with controllable hydrophobicity. Journal of Materials 化学 B
12. Wanyin Zhai, Hongxu Lu, Chengtie Wu, Lei Chen, Xiaoting Lin, Kawazoe Naoki, Guoping Chen*, Jiang Chang*. Stimulatory effects of the ionic products from Ca-重症肌无力Si bioceramics on both osteogenesis and angiogenesis in vitro. Acta Biomaterialia
13. Haiyan Li, Jiang Chang*. Bioactive silicate materials stimulate angiogenesis in fibroblast and endothelial cell co-culture system through paracrine effect. Acta Biomaterialia
14. Kaili Lin, Lunguo Xia, Jinbo Gan, Zhiyuan Zhang, Hong Chen*, Xinquan Jiang*, Jiang Chang*. Tailoring the Nanostructured Surfaces of Hydroxya patite Bioceramics to Promote Protein Adsorption, Osteoblast Growth, and Osteogenic Differentiation. ACS Applied Materials\u0026 Interfaces
15. Kaili Lin, Lunguo Xia,Haiyan Li, Xinquan Jiang,Haobo pan,Yuanjin Xu,William W Lu, Zhiyuan Zhang*, Jiang Chang*. Enhanced osteoporotic bone regeneration by 锶substituted 一水合醋酸钙 silicate bioactive ceramics. Biomaterials
16. Chengtie Wu, Yinghong Zhou, Jiang Chang*, Yin Xiao*. Delivery of dimethyloxallyl glycine in mesoporous bioactive glass scaffolds to improve angiogenesis and osteogenesis of human bone marrow stromal cells. Acta Biomaterialia
17. Yan Han, Qiongyu Zeng, Haiyan Li*, Jiang Chang*. The 钙 silicate/alginate composite: preparation and evaluation of its behavior as bioactive injectable hydrogels. Acta Biomaterialia
18. Lunguo Xia, Kaili Lin, Xinquan Jiang, Yuanjin Xu, Maolin Zhang, Jiang Chang*, Zhiyuan Zhang*. Enhanced osteogenesis through nano-structured surface 设计 of macroporous 羟基磷灰石 bioceramic scaffolds via activation of ERK and p38 MAPK signaling pathways. Journal of Materials 化学
19. Chengtie Wu, Jiang Chang*, Wei Fan*. Bioactive mesoporous 钙silicate nanoparticles with excellent mineralization ability, osteostimulation, drug-delivery and antibacterial properties for filling apex root of tooth. Journal of Materials 化学
20. Chengtie Wu, Yinghong Zhou, Chucheng Lin, Jiang Chang*, Yin Xiao*. 锶containing mesoporous bioactive glass scaffolds with improved osteogenic/cementogenic differentiation of periodontal ligament cells for periodontal tissue engineering. Acta Biomaterialia
21. Meili Zhang, Chengtie Wu, Haiyan Li, Jones Yuen, Jiang Chang*, Yin Xiao*. Preparation, characterization and in vitro angiogenic capacity of 钴 substituted b-tri钙 磷酸盐 ceramics. Journal of Materials 化学
22. Zhaoyong Zou, Xiaoguo Liu, Lei Chen, Kaili Lin*, Jiang Chang*. Dental enamel-like hydroxyapatite transformed directly from monetite. Journal of Materials Chemistry
23. Yuandong Dou, Chengtie Wu, Jiang Chang*. Preparation, mechanical property and cytocompatibility of poly (L-lactic acid)/一水合醋酸钙 silicate nanocomposites with controllable distribution of calcium silicate nanowires
24. Wanyin Zhai, Hongxu Lu, Lei Chen, Xiaoting Lin, Yan Huang, Kerong Dai, Kawazoe Naoki, Guoping Chen*, Jiang Chang*. Silicate bioceramics induce angiogenesis during bone regeneration. Acta Biomaterialia
25. Botao Song, Chengtie Wu, Jiang Chang*. Dual drug release from electrospun poly(lactic-co-glycolic acid)/mesoporous silica nanoparticles composite mats with distinct release profiles. Acta Biomaterialia
26. Chen Wang, Xue Yang, Kaili Lin, Jianxi Lu, Jiang Chang*, Jiao Sun*.The enhancement of bone regeneration by the combination of osteoconductivity and osteostimulation using composite bioceramics. Acta Biomaterialia
27. Huijie Gu, Fangfang Guo,Xiao Zhou,Lunli Gong, Yun Zhang, Wanyin Zhai, Lei Chen, Lian Cen, Shuo Yin, Jiang Chang*, Lei Cui*. Ionic products from akermanite dissolution stimulate osteogenic differentiation of human adipose-derived stem cells via activation of ERK pathway. Biomaterials
28. Kaili Lin, Yanling Zhou, Yue Zhou, Haiyun Qu, Feng Chen, Yingjie Zhu, Jiang Chang*. Biomimetic 羟基磷灰石 porous microspheres with co-substituted essential trace elements: Surfactant-free hydrothermal synthesis,enhanced degradation and drug release. Journal of Materials 化学
29. Liang Wu, Yuandong Dou, Kaili Lin, Wanyin Zhai, Wenguo Cui, Jiang Chang*. Hierarchically structured nanocrystalline hydroxyapatite assembled hollow fibers as a promising protein delivery system. Chemical Communications
30. Kaili Lin, Xiaoguo Liu, Jiang Chang*, Yingjie Zhu, Facile Synthesis of 羟基磷灰石 Nanoparticles, Nanowires and Hollow Nano-structured Microspheres using Similar Structured Hard-precursors. Nanoscale
31. Yuandong Dou, Kaili Lin, Jiang Chang*. Polymer nanocomposites with controllable distribution and arrangement of inorganic nanocomponents. Nanoscale
32. Wanyin Zhai, Xiqin Lü, Jiang Chang*, Yanlin Zhou, Hongfeng Zhang, 槲皮素 crosslinked porcine heart valve matrix: mechanical property, stability, anti-calcification and cytocompatibility, Acta Biomaterialia
33. Zhiguang Huan, Jiang Chang*. Novel bioactive composite bone cements based on β-tricalcium 磷酸盐-monocalcium phosphate monohydrate composite cement system. Acta Biomaterialia
34. Yan Huang, Xiaogang Jin, Xiaoling Zhang, Hongli Sun, Jinwen Tu, Tingting Tang, Jiang Chang*, Kerong Dai.In vitro and in vivo evaluation of akermanite bioceramics for bone regeneration. Biomaterials
35. Daming Zhang, Jiang Chang*. Electrospinning of Three-Dimensional Nanofibrous Tubes with Controllable Architectures. Nano Letters
36. Qihai Liu, Lian Cen, Shuo Yin, Lei Chen, Guangpeng Liu, Jiang Chang*, Lei Cui*. A comparative study of proliferation and osteogenic differentiation of adipose-derived stem cells on akermanite and β-TCP ceramics, Biomaterials
37. Songfeng Xu, Kaili Lin, Zhen Wang*, Jiang Chang*, Lin Wang, Jianxi Lu, Congqin Ning. Reconstruction of calvarial defect of rabbits using porous 钙 silicate bioactive ceramics. Biomaterials
38. Daming Zhang, Jiang Chang*. Patterning of electrospun fibers using electroconductive templates. Advanced Materials
39. Zhiguang Huan, Jiang Chang*. Self-setting properties and in vitro bioactivity of the calcium sulfate hemihydrate/tricalcium silicate composite bone cements. Acta Biomaterialia
40. Faming Zhang, Jiang Chang*, Jianxi Lu, Kaili Lin, Congqin Ning. Bioinspired Structure of Bioceramics for Bone Regeneration in Load Bearing Sites. Acta Biomaterialia
41. Hongli Sun, Chengtie Wu, Kerong Dai*, Jiang Chang*, Tingting Tang, Proliferation and osteoblastic differentiation of human bone marrow-derived stromal cells on akermanite bioactive ceramics. Biomaterials
42. Wanyin Zhai, Jiang Chang*, Kaili Lin, Junyin Wang, Qiang Zhao, Xiaoning Sun. Crosslinking of decellularized porcine heart valve matrix by procyanidins. Biomaterials
43. Wei Xia, Jiang Chang*. Well-ordered mesoporous bioactive glasses (MBG): a promising bioactive drug delivery system. Journal of Controlled Release
44. Chengtie Wu, Jiang Chang*, Junying Wang, Shiyu Ni, Wanyin Zhai. Preparation and Characteristics of a 钙 镁 Silicate (Bredigite) Bioactive Ceramic. Biomaterials
45. Wenyuan Zhao, Wanyin Zhai, Zheng Wang, Junying Wang, Jiang Chang*. The self-setting property and in vitro bioactivity of tricalcium silicate. Biomaterials.
46. Haiyan Li, Jiang Chang*. Fabrication and characterization of bioactive 硅灰石/PHBV composite scaffolds. Biomaterials
参考资料
常江.中国科学院上海硅酸盐研究所.2014-04-17