陶金
陶金,教授,东吴学者,苏州大学博士生导师,生理学与神经科学系主任,1997年本科毕业于南京医科大学,2007南京医科大学药理学系(新加坡国立大学联合培养博士生),医学博士,
2007-2009年华盛顿大学医学院疼痛研究中心博士后研究。2012年入选东吴学者。2011年起任苏州大学医学部生理学与神经生物学系主任。
人物经历
2013.05 – 目前 苏州大学医学部生理学与神经生物学系,主任、教授、博导、东吴学者;苏州大学神经科学研究所PI
2009.06 –2013.05 苏州大学医学部神经生物学系,教授、东吴学者
2007.08 –2009.06 美国圣路易斯华盛顿大学医学院疼痛研究中心,博士后
2005.08 - 2007.07 新加坡国立大学/国家神经科学研究所,助理研究员
2002.09 - 2007.07 南京医科大学药理学系(NUS联合培养博士生),医学博士
1997.09 - 2002.06 南京医科大学临床医学系,医学学士
主要贡献
主要成就
1.国家自然科学基金(81171056),主持,在研
2.国家自然科学基金(NSFC-CNRS项目,81311130114),主持,在研
3.国家自然科学基金(30900437),主持,已结题
4.教育部留学回国人员启动基金,第40批,主持,在研
5.江苏省自然科学基金,BK2011293,主持,在研
6.江苏省高校自然科学基金, 09KJB180008,主持,已结题
7. 东吴学者计划资助,主持,在研
出版著作
1.Guo Q, Jiang YJ, Jin H, Jiang XH, Gu B, Zhang YM, Wang JG, Qin ZH, Tao J*. Modulation of A-type K+ channels by the short-chain cobrotoxin through the protein kinase C-delta isoform decreases membrane excitability in dorsal root ganglion neurons. Biochem Pharmacol2013, 85(9):1352-62.
2.Zhang Y, Jiang X, Snutch TP, Tao J*. Modulation of low-电压activated T-type Ca²⁺channels. Biochim Biophys Acta2013, 1828(7):1550-9.
3.Zhang Y, Jiang D, Zhang Y, Jiang X, Wang F, Tao J*. Neuromedin U type 1 receptor stimulation of A-type K+ current requires the βγ subunits of Go protein, protein kinase A, and extracellular signal-regulated kinase 1/2 (ERK1/2) in sensory neurons. J Biol Chem2012, 287(22):18562-72.
4.Zhang Y, Zhang J, Jiang D, Zhang D, Qian Z, Liu C, Tao J*. Inhibition of T-type Ca²⁺channels by endostatin attenuates human glioblastoma cell proliferation and migration. Br J Pharmacol2012, 166(4):1247-60.
5.Zhang L, Zhang Y, Jiang D, Reid PF, Jiang X, Qin Z, Tao J*.Alpha-cobratoxin inhibits T-type 钙 currents through muscarinic M4 receptor and Gο-protein βγ subunits-dependent protein kinase A pathway in dorsal root ganglion neurons. Neuropharmacology2012, 62(2):1062-72.
6.Zhang Y, Zhang L, Wang F, Zhang Y, Wang J, Qin Z, Jiang X, Tao J*. Activation of M3 muscarinic receptors inhibits T-type Cachannel currents via pertussis toxin-sensitive novel protein kinase C pathway in small dorsal root ganglion neurons. Cell Signal2011, 23: 1057-1067.
7.Wang F, Zhang Y, Jiang X, Zhang Y, Zhang L, Gong S, Liu C, Zhou L, Tao J*. Neuromedin U inhibits T-type Cachannel currents and decreases membrane excitability in small dorsal root ganglia neurons in mice. Cell 一水合醋酸钙2011, 49, 12-22.
8.Xu G, Wang F, Jiang X, Tao J*.Aquaporin 1, a potential therapeutic target for 偏头痛 with aura. Molecular Pain2010, 6, 68-76. (Highly Accessed)
9.Zhang Y, Jiang D, Zhang J, Wang F, Jiang X, Tao J*. Activation of neuromedin U type 1 receptor inhibits L-type Cachannel currents via phosphatidylinositol 3-kinase-dependent protein kinase C epsilon pathway in mouse hippocampal neurons. Cell Signal2010, 22, 1660-1668.
10. Tao J*, Zhang Y, Huang H, Jiang X.Activation of corticotropin-releasing factor 2 receptor inhibits Purkinje neuron P-type 钙 currents via Gα-dependent PKC eposilon pathway. Cell Signal2009, 21, 1436-1443.
11. Tao J, Hildebrand ME, Liao P, Liang MC, Tan G, Li S, Snutch TP, Soong TW. Activation of corticotropin-releasing factor receptor 1 selectively inhibits Ca3.2 T-type 钙 channels. 摩尔 Pharmacol2008,73,1596-1609.
12. Tao J, Zhang Y, Li S, Sun W, Soong TW. Tyrosine kinase-independentinhibition bygenistein on spermatogenic T-type calcium channels attenuates mouse sperm motility and acrosome reaction. Cell 钙2009, 45, 133-143.
13.Zhang Y, Tao J*, Huang H, Ding G, Cheng Y, Sun W. Effects of celecoxib on 电压gated calcium channels inratpheochromocytomacells. Pharmacol Res2007,56,267-274.
14. Tao J, Zhang Y, Soong TW, Li S. Expression of urocortin 2 and its inhibitory effects on intracellular Cavia L-type 电压gated 钙 channels in ratpheochromocytomacells. Neuropsychopharmacology2006, 31, 2600-2609.
15. Tao J, Xu H, Yang C, Liu CN, Li S. Effect of Urocortin on L-type calcium currents in adult rat ventricular myocytes. Pharmacol Res2004, 50, 471-476.
获奖记录
教改及奖励:
1.国家级大学生创新项目2项,导师
2.江苏省大学生创新创业项目1项,导师
3.苏州大学大学生课外学术科研基金重大项目1项,导师
5.苏州大学医学部教改项目1项,主持
6.江苏省科学技术奖三等奖,排名第三